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Infertility Powder Letrozole Orally

Infertility Powder Letrozole Orally

What is letrozole, and how does it work (mechanism of action)? Letrozole is an oral, anti-estrogen drug that is used for treating postmenopausal women with breast cancer. The growth of some breast cancers in postmenopausal women is promoted by estrogens that circulate in the blood, and the...

  • Features & Specification

    What is letrozole, and how does it work (mechanism of action)?

    Letrozole is an oral, anti-estrogen drug that is used for treating postmenopausal women with breast cancer. The growth of some breast cancers in postmenopausal women is promoted by estrogens that circulate in the blood, and the adrenal glands are the main source of these circulating estrogens. Letrozole inhibits the enzyme in the adrenal glands that produces the estrogens, estradiol and estrone. Letrozole was approved by the FDA in 1997.

     

    What is the dosage for letrozole?

    The recommended dose is 2.5 mg once daily with or without food. Patients with severe liver impairment should receive 2.5 mg every other day.

     

    Which drugs or supplements interact with letrozole?

    Tamoxifen reduces blood levels of letrozole when both drugs are administered together. However, in clinical studies the benefit of letrozole was not reduced when administered immediately after tamoxifen. Letrozole is an anti-estrogen drug. Therefore, estrogen containing products counteract the effect of letrozole.

     

    What are the side effects of letrozole?

    The most common side effects with letrozole are:

    nausea,

    vomiting,

    fatigue,

    headache,

    muscle aches,

    diarrhea,

    constipation, and

    chest pain.

     

    What else should I know about letrozole?

    What preparations of letrozole are available?

    Tablets: 2.5mg.

     

    How should I keep letrozole stored?

    Tablets should be stored at room temperature, 15 C - 30 C (59 F - 86 F)

     

     

     


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