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Top AICAR Powder SARMS Acadesine Fitness

Top AICAR Powder SARMS Acadesine Fitness

AICAR Description AICAR (powder) Details: CAS ID: 2627-69-2 Synonyms: Acadesine; Aminoimidazole carboxamide ribonucleotide; AICA ribonucleotide; ZMP; 5-Amino-1-β-D-ribofuranosyl-imidazole-4-carboxamide. Molecular Formula: C9H15N4O8P Molecular Weight: 338.211162 Appearance: White Powder Purity:...

  • Features & Specification

    AICAR Description

    AICAR (powder) Details:
    CAS ID: 2627-69-2
    Synonyms: Acadesine; Aminoimidazole carboxamide ribonucleotide; AICA ribonucleotide;
    ZMP; 5-Amino-1-β-D-ribofuranosyl-imidazole-4-carboxamide.
    Molecular Formula: C9H15N4O8P
    Molecular Weight: 338.211162
    Appearance: White Powder
    Purity: 99.21%
    Melting point: 213-214 °C
    Storage: Before reconstitution (lyophilized / freeze dried powder):
    Can be stored in the refrigerator (2°C to 8°C = 35°F to 47°F) for 36 months.
    Can be stored at room Temperature (up to 37°C = 99°F) for 90 days.
    After reconstitution (liquid):
    Can be stored in the refrigerator (2°C to 8°C = 35°F to 47°F) for 5 days.
    Transportion time at room temperature has not effect on product quality degradation.

    Solubility: Soluble in DMSO (15 mg/ml); or water (15 mg/ml).


    AICAR Overview - WHAT IS AICAR?

    5-Aminoimidazole-4-carboxamide ribonucleotide, AICAR for short, it is an analog of AMP (adenosine monophosphate), which stimulates AMPK (AMP-dependent protein kinase) processes in the body. As a matter of fact, AICAR works best as part of an endurance stack, and it has been used by athletes as a performance enhancing compound in sports, where endurance is needed. We are offering AICAR in raw powder form.


    AICAR/Acadesine Application 

    lose weight

    AICAR is a peptide that is a generation of inosine in the intermediate, and metabolic regulation is directly related. The most important mechanism known to AICAR is its ability to block enzymes at both intracellular and extracellular levels, which in turn allows accelerated stimulation of glucose uptake and increased protein kinase in skeletal muscle tissue. These two functions allow more energy conversion, which helps to burn fat and maintain the output of the activity. Scientists and athletes / bodybuilders are interested in this.

     

    AMP activates protein kinase 

    The main mechanism of AICAR is to activate AMPK (AMP activates protein kinase). Thus, activating AMPK can make the same cellular mechanism, which can be said to be open, as cells are consumed by energy, such as strong or low calorie intake.

    AICAR uses metabolic pathways to block certain enzymes, which allows AMP to activate protein kinases. This can be explained by layman: Once you have eaten a lot of AICAR, it will deceive your body at the cellular level and think that this exercise has just been completed. Since the body considers that a considerable amount of exercise has been carried out, the cell energy cycle begins to transform the fuel source, such as fatty acids, to output the energy that is considered to be consumed in motion. This can directly affect the level of endurance activity and the sustainability of the activity. Insulin sensitivity is also considered a behavior of AICAR, because the body will think that it is only experienced a series of exercises. 

     

    Prevent ischemic injury 

    AICAR has been shown to prevent ischemic injury. This type of injury is directly related to the limits of blood on the tissue, which may result in the lack of oxygen and glucose required to maintain tissue vitality. This can lead to thrombosis, embolism and vasoconstriction. AICAR can be used as a stable peptide for ischemic seizures and can cause appropriate blood flow to the heart (heart). This feature is very interesting because AICAR can be used fundamentally for the treatment of heart muscle heart attacks. This may reduce the likelihood of ischemic injury. In animal studies using peptide AICAR, abnormal growth in cardiac tissue and heart valve function has also changed, which is disadvantageous.

     

    AICAR/Acadesine COA 

    Item

    Specification

    Result

    Appearance

    White   powder

    Complies

    Related substance (HPLC)

    Total   impurity ≤0.5%
      Max single impurity ≤0.1%

    0.2%
      0.06%

    Odor

    Characteristic

    Complies

    Assay

    99%

    99.8%

    Sieve analysis

    100%   pass 80 mesh

    Complies

    Loss on Drying
      Residue on Ignition

    ≤1.0%
      ≤1.0%

    0.12%
      0.09%

    Heavy Metal

    <10ppm

    Complies

    As

    <0.1ppm

    0.05ppm

    Pb

    <0.1ppm

    0.05ppm

    Cd

    <0.1ppm

    0.05ppm

    Residual Solvents

    <100ppm

    Complies

    Residual Pesticide

    Negative

    Complies

    Microbiology

    Total Plate Count

    <1000cfu/g

    Complies

    Yeast & Mold

    <100cfu/g

    Complies

    E.Coli

    Negative

    Complies

    Salmonella

    Negative

    Complies

    AICAR/Acadesine Function: 

    AICAR is an adenosine analog that selectively activates AMP-activated protein kinase (AMPK). AMPK regulates lipid and glucose metabolism to maintain cellular energy homeostasis (Hardie and Carling).

    AICAR can play a hand in boosting these processes because it contains the ability to penetrate cardiac cells and block the production of enzymes tied to regulating glucose intake and energy expulsion. With these regulatory enzymes inhibited, the affected cells can in turn boost the amount of glucose that can be received, and it can also increase its level of energy conversion. Additionally, the peptide’s presence has been determined to aid in lowering programmed cell death, a process that is also known as apoptosis.

     

    AICAR/Acadesine Dosage: 

    New users:25mg/day 

    Advanced users: those who had already experienced with steroids, peptides or HGH:50mg/day

    Competitors and Professionals:75mg/day,divide the injections during the day

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