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Ace031 Peptides Steroid Ace Weight Loss 1mg Ace-031

Ace031 Peptides Steroid Ace Weight Loss 1mg Ace-031

ACE031 is a soluble fusion protein that has been shown to increase muscle mass and strength in research studies. ACE-031 is being studied as a treatment for metabolic diseases, renal neoplasms of childhood, cardiovascular anomalies, age-related muscle loss, and cancer treatment related muscle loss and neuromuscular diseases.

  • Features & Specification

    Basic Info

    Name: Ace 031

    Spe: 1mg/Vial

    Appearance: White Powder

    MOQ: 1 Vial

    Usage: Bodybuilding

    Payment Method: Western Union, Money Gram, Bitcoin, T/T, .

    Shipping Method: FedEx, DHL, EMS or by Sea

    Delivery Time: Within 3 Days After Payment

    Place of Origin: Shenzhen

    Export Markets: Global

    Trademark: Sendi

    Transport Package: Alumiuim Foil or as Customer′s Requirement

    Specification: USP

    Origin: Jiangsu, China(Mainland)

    HS Code: 2937290090

    Product Description


    Ace031 Peptides Steroid ace Weight Loss 1mg Ace 031

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    Product Description:
    ACE-031 is intended for research purpose only. ACE-031 should not be used for human consumption, diagnostic, therapeutic procedures, agricultural and veterinary purposes.

    ACE-031 is a soluble fusion protein that has been shown to increase muscle mass and strength in research studies. ACE-031 is being studied as a treatment for metabolic diseases, renal neoplasms of childhood, cardiovascular anomalies, age-related muscle loss, and cancer treatment related muscle loss and neuromuscular diseases.

    ACE-031 is a biologic therapeutic, based on activin receptor type IIB (ActRIIB). The molecule inhibits signaling via the ActRIIB receptor binding and increase muscle mass and strength. ACE-031 is a recombinant fusion protein that is artificially synthesized by fusion of standard antibody and a portion of ActRIIB receptor. The recombinant fusion protein eliminates myostatin and other biomolecules that limit muscle strength or growth.


    PEPTIDE INFORMATION



     Product Name:

    ACVR2B / ACE-031 (untagged/tag free)

     Unit size:

    1 mg/vial

     CAS NO.:

     

     Synonyms:

    Activin Receptor Type-2B, Activin Receptor Type IIB, ACTR-IIB, ACE-031

     Sequence:

    GNCWLRQAKN GRCQVLYKTE LSKEECCSTG RLSTSWTEED VNDNTLFKWM IFNGGAPNCI PCKETCENVD CGPGKKCRMN KKNKPRCVCA PDCSNITWKG PVCGLDGKTY RNECALLKAR CKEQPELEVQ YQGRCKKTCR DVFCPGSSTC VVDQTNNAYC VTCNRICPEP ASSEQYLCGN DGVTYSSACH LRKATCLLGR SIGLAYEGKC IKAKSCEDIQ CTGGKKCLWD FKVGRGRCSL CDELCPDSKS DEPVCASDNA TYASECAMKE AACSSGVLLE VKHSGSCN

     Purity:

    ≥98% (HPLC)

     Physical State:

    Lyophilized Powder

     Solubility:

    Soluble in water or 1% acetic acid

     Storage:

    Lyophilized peptides although stable at room temperature for 3 months, should be stored desiccated below -18°C. Upon reconstitution of the peptide it should be stored at 4°C between 2-21 days and for future use below -18°C.
     



    Summary Results
     
    -ACE-031 was well tolerated at all dose levels and demonstrated a linear pharmacokinetic profile with an average half-life ranging from 10-15 days
     
    -Single doses of ACE-031 at 1 mg/kg and 3 mg/kg produced dose-dependent increases in lean body mass measured by dual energy X-ray absorptiometry (DXA) as early as day 15 that were sustained through day 57
     
    -Subjects given single doses of placebo had a 0.2% decrease in lean body mass at day 57 compared to a 2.4% increase in subjects receiving 1 mg/kg ACE-031 and a 2.6% increase in subjects receiving 3 mg/kg ACE-031
     
    -Subjects given single doses of placebo had a 0.2% decrease in muscle volume assessed by MRI at day 29 compared to a 3.5% increase in subjects receiving 1 mg/kg ACE-031 and 5% increase in subjects receiving 3 mg/kg ACE-031
     
    -ACE-031 favorably affected biomarkers of fat mass (increased adiponectin and decreased leptin) and bone formation and resorption (increased bone-specific alkaline phosphatase (BSAP) and decreased C-terminal type 1 collagen telopeptide (CTX) at doses of 1 and 3 mg/kg
     
    "ACE-031 holds great potential as a treatment for patients suffering from neuromuscular diseases such as muscular dystrophy and amyotrophic lateral sclerosis (ALS)," said John Knopf, Ph.D., Chief Executive Officer of Acceleron. "We are moving forward with great confidence and excitement with the ACE-031 program as well as our overall muscle franchise."
     
    Muscle is increasingly recognized as central to many biological processes and plays a major role in human health. The loss of muscle mass and strength is ultimately directly related to the cause of death in neuromuscular diseases such as muscular dystrophy and amyotrophic lateral sclerosis. Severe muscle loss in cancer leads to serious complications and a poor prognosis. Muscle loss is a natural consequence of aging, similar to bone loss, resulting in decreased muscle strength (frailty), reduced mobility and an increased risk of a fall and broken bones. In metabolic diseases, an imbalance of diet, energy utilization and skeletal muscle leads to poor metabolic function. By increasing muscle mass there is a corresponding decrease in fat mass and improvements in metabolic function.
     
    About ACE-031
     ACE-031, a soluble fusion protein based on the activin receptor type IIB (ActRIIB), is a biologic therapeutic that inhibits signaling through the ActRIIB receptor. By preventing signaling though ActRIIB, ACE-031 increases muscle mass and strength. In numerous and varied animal models of disease, ACE-031 significantly increased muscle mass and muscle strength. ACE-031, and a related molecule ACE-435, have shown encouraging preclinical results in animal models of age-related muscle loss, neuromuscular disease, cancer treatment-related muscle loss and metabolic diseases. ACE-031 is currently being studied in a Phase 1 multiple dose clinical trial in healthy volunteers. ACE-435 is expected to enter clinical trials in 2010.
     

    The quality control process
    1)Purchasing
    Thorough market research, understand the price of raw materials and performance.To the procurement source to understand fully, and fully guarantee the quality of the procurement of raw materials.
    2) Inspection
    Four steps: sampling, sample pretreatment, measuring and data processing.
    3) Producing
    a)Each operator must do self-inspection of products and make the corresponding inspection records.
    b)Full-time inspectors through check the operator self-inspection, and review and sign in the corresponding record. Full-time inspection is responsible for inspection of finished product, and make the finished product incoming inspection records.
    4) Before selling 
    Test result can be provided before selling.
    Third-party detection institution is allowed if you are not satisfied with test results.



    After-sales service:
    1.We will ship the goods within 3days after get your payments.If you want to cancel or change order, please tell me within 24hours after you finish the payment...So we both can make the best of the bad bargain.
    2.We will ship the goods that you order from us by EMS, DHL, UPS, or FedEx.We will decided to choose which courier depend on Different countries.To find the best way to delivery the goods for you.
    3.As usual you can get the goods with in 4-7days.If the goods were lost or not received for other reasons, please contact me Immediately.
    Factory price, pure injection, best credit.



    Contact method:
    Garry

    Wickr: garry3344

    Email: garry@yccreate.com

    Whats app: +86 18702759822


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