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Topical Hydrochloride Pain Killer Prilocaine HCL

Topical Hydrochloride Pain Killer Prilocaine HCL

Basic Data Prilocaine HCl Description Propitocaine hydrochloride is a local anesthetic of the amino amide type first prepared by Claes Tegner and Nils Lö Fgren. In its injectable form, it is often used in dentistry. It is also often combined with lidocaine as a preparation for dermal anesthesia...

  • Features & Specification

    Basic Data 

    Product Name

    Prilocaine hydrochloride

    Trade Name

    Citanest

    CAS

    1786-81-8

    Molecular formula

    C13H21ClN2O

    EINECS

    217-244-0

    Molecular Weight

    256.77

    Assay

    99%

    Shipping

    Express Courier

    Standard

    Enterprise Standard

    Use

    Local anesthetics, long duration, lower toxicity,
    chemicals that are also small suitable for epidural anesthesia,
    block anesthesia and infiltration anesthesia, etc.

     

    Prilocaine HCl Description

    Propitocaine hydrochloride is a local anesthetic of the amino amide type first prepared by Claes Tegner and Nils Lö Fgren. In its injectable form, it is often used in dentistry. It is also often combined with lidocaine as a preparation for dermal anesthesia (lidocaine/prilocaine or EMLA), for treatment of conditions like paresthesia. As it has low cardiac toxicity, it is commonly used forintravenous regional anaesthesia.

    In some patients, a metabolite of prilocaine may cause the unusual side effect of methemoglobinemia, which may be treated with methylene blue.

    Local anesthetic is a substance that causes loss of sensation only to the area to which it is applied without affecting consciousness. Most local anesthetics structures have amino-ester or an amino-amide group which are linked to hydrophilic (secondary or tertiary amine) and to hydrophobic group (aromatics) on the other side.

    Local anesthetics, long duration, lower toxicity, chemicals that are also small Suitable for epidural anesthesia, block anesthesia and infiltration anesthesia, etc.image001.jpg 

    Prilocaine Hydrochloride Description:
    1. Prilocaine HCl a local anesthetic agent of the amide family, used for nerve block, epidural, and regional anesthesia. It is not used for spinal or topical anesthesia.
    2. Prilocaine hydrochloride is about half as toxic as lidocaine but, because methemoglobinemia is a possible reaction to its administration, is not used for patients with hypoxic conditions of any kind.
    3. Prilocaine Hydrochloride is an FDA approved amino amide type local anesthetic. It is primarily used as a nerve block in dental surgery in the injectable form.
    4. Prilocaine Hydrochloride is also used in topical anesthetic creams. It's often combined with Lidocaine.
    5. However, Prilocaine is less toxic and causes less vasodilation than Lidocaine.
    6. As a topical anesthetic, Prilocaine combined with Lidocaine deadens the nerve endings in the skin.
    7. Prilocaine Hydrochloride can safely be used on mucous membranes including genital areas. It's also safe for pediatric use.
    8. A local anesthetic of the amino ester group that is primarily used as a topical anesthetic.Also used to control the pain of intramuscular injection of penicillin as well as in dentistry.Non Caine local anesthetic.
    9. Prilocaine hydrochloride is a kind of local anesthetics, for local anesthesia, nerve block etc, can block the conduction of nerve fibers with anesthetic effect, strong function, low toxicity, and no addiction, but the skin, mucous membrane penetration force is weak, not suitable for surface anesthesia, clinically used to infiltration, spine and conduction anesthesia.

    Prilocaine HCl COA 

    Product name

    Prilocaine hydrochloride

    CAS No.

    1786-81-8

    Packing

    25KG/Cardboard drum

    Date of manufacturing

    11th, March, 2017

    Shelf life

    10th, March, 2019

    Standard adopted

    USP36

    Items

    Specification

    Results

    Description

    White crystalline powder

    Complies

    Solubility

    Freely soluble in water and in alcohol,slightly soluble in chloroform,   very slightly soluble in acetone, practically insoluble in ether

    Complies

    Identification

    Should be positive response

    Complies

    Melting Point

    166~169ºC

    166~168ºC

    Loss on drying

    ≤ 0.3%

    0.13%

    Residue on ignition

    ≤0.1%

    0.03%

    Heavy metals

    ≤0.002%

    <0.002%

    Residual solvents

    Should comply with the standard

    Complies

    Assay

    99.0% ~101.0%(on dried basis)

    99.46%

    Conclusion

    Qualified


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