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Topical Anesthetic Drugs Propitocaine Hydrochloride

Product introduction Best Propitocaine hydrochloride Whatsapp:+8618123940985 Skype:shucanlynn Emial:demi@chembj.com Sample:Available Price: Negotiable Customized blend :Available Standard: SGS,ISO9001,KOSHER Product Name: Propitocaine Hcl Whatsapp:+8618123940985 Propitocaine Hcl Alias Prilocaine...

  • Features & Specification

    Product introduction

    Best Propitocaine hydrochloride

    Whatsapp:+86 18123940985

    Skype:shucanlynn

    Email:demi@chembj.com

    Sample:Available

    Price: Negotiable

    Customized blend :Available

    Standard: SGS,ISO9001,KOSHER

     

    Product Name:Propitocaine Hcl

    image002.jpg

    Alias Prilocaine Hcl;Propitocaine Hydrochloride

    CAS  1786-81-8

    MF   C13H21ClN2O

    Apperance    white Powder

    Assay     99%

    Grade    Pharmaceutical Grade

    Resend:Resend Policy

    Payment Method: Banktransfer,MoneyGram,Western Union,Bitcoin

    Free Sample:       Yes

    Delivery:       DHL,FEDEX,EMS,TNT And So On

     

    What is Propitocaine hydrochloride ? 

    Propitocaine hydrochloride is a local anesthetic of the amino amide type. In its injectable form, it is often used in dentistry. It is also often combined with lidocaine as a preparation for dermal anesthesia (lidocaine/prilocaine or EMLA), for treatment of conditions like paresthesia. As it has low cardiac toxicity, it is commonly used forintravenous regional anaesthesia.

    In some patients, a metabolite of prilocaine may cause the unusual side effect of methemoglobinemia, which may be treated with methylene blue. 


    Propitocaine hydrochloride Usage:

    Prilocaine is a local anesthetic of the amino amide type. Prilocaine is often used in dentistry. Prilocaine is also often combined with lidocaine as a preparation for dermal anesthesia (lidocaine/pril ocaine or EMLA), for treatment of conditions like paresthesia.
    Anesthetic (local). 


    Prilocaine Hydrochloride Injection 

    Mechanism of Action 

    Prilocaine stabilizes the neuronal membrane by inhibiting the ionic fluxes required for the initiation and conduction of impulses, thereby effecting local anesthetic action.

     

    Onset and Duration of Action 


    When used for infiltration injection in dental patients, the time of onset of anesthesia averages less than 2 minutes with an average duration of soft tissue anesthesia of approximately 2 hours. 

    O-toluidine has been found to produce methemoglobin both in vitro and in vivo (see Adverse Reactions). 

    Since prilocaine is metabolized in both the liver and kidneys, liver and kidney dysfunction may alter the kinetics of prilocaine. 


    Like other local anesthetics, the plasma binding of prilocaine may depend on the drug concentration. At 0.5 to 1.0 mg/mL, it binds 55% of the protein. 

    Presumably through passive diffusion, prilocaine crosses the blood-brain barrier. 

    Factors such as acidosis and the use of CNS stimulants and inhibitors affect CNS levels of prilocaine required to produce significant systemic effects. In rhesus monkeys, arterial blood levels of 20 mg/mL have proven to be the threshold for convulsive activit 


    Prilocaine Hydrochloride Injection, USP, 4% is a sterile, non pyrogenic isotonic solution that contains a local anesthetic agent and is administered parenterally by injection.

     

     

    Please feel free contact me

    Whatsapp:+86 18123940985

    Skype:shucanlynn

    Emial:demi@chembj.com

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