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Raw Levobupivacaine Hydrochloride

Raw Levobupivacaine Hydrochloride

Levobupivacaine Quick Details Levobupivacaine Description: Levobupivacaine (rINN) is a local anaesthetic drug belonging to the amino amide group. It is the S-enantiomer of bupivacaine.It is the hydrochloride salt of levobupivacaine, an amide derivative with anesthetic property. Levobupivacaine...

  • Features & Specification

    Levobupivacaine Quick Details

    Product   Name

    Levobupivacaine   hydrochloride

    Alias

    Levobupivacaine HCL, Chirocaine

    CAS

    27262-48-2

    MF

    C18H29ClN2O

    MW

    324.89

    Purity

    99.00%

    Grade

    Pharmaceutical   Grade

    Appearance

    White   crystalline powder.

    Brand   Nmae

    HKYC

    Standard

    USP

    Shelf   life

    2 years

    Stradge

    Store   in sealed containers at cool & dry place. Keep away from light, moisture,   pest infestation

    Stock

    Mass   Stock

    Packing   Methods

    designed   disguised packing ways, 100% pass custom guarantee

    Delivery   time

    within   18 hours after payment confirmed

    Payment

    T/T,   Western Union,Money Gram , Bitcoin

    Usage

    Levobupivacaine   is a local anaesthetic drug belonging to the amino amide group.

     

    Levobupivacaine Description:

    Levobupivacaine (rINN) is a local anaesthetic drug belonging to the amino amide group. It is the S-enantiomer of bupivacaine.It is the hydrochloride salt of levobupivacaine, an amide derivative with anesthetic property.

    Levobupivacaine reversibly binds voltage-gated sodium channels to modulate ionic flux and prevent the initiation and transmission of nerve impulses (stabilizing neuronal membrane), thereby resulting in analgesia and anesthesia. In comparison with racemic bupivacaine, levobupivacaine is associated with less vasodilation and has a longer duration of action.

    Levobupivacaine hydrochloride is a sodium channel blocker used as a long-acting local anaesthetic for epidural anesthesia. Levobupivacaine is the isomer of bupivacaine, with efficacy similar to that of bupivacaine with a reduced risk of cardiotoxicity.

     

    Levobupivacaine Application:

    Levobupivacaine is a local anaesthetic drug belonging to the amino amide group. It is the S-enantiomer of bupivacaine. Levobupivacaine hydrochloride is commonly marketed by Abbott under the trade name Chirocaine. Bupivacaine is an amide-type local anaesthetic. Although it blocks neuro transmission, its membrane stabilising action also affects the myocardium. This can cause fatal cardiotoxicity. As bupivacaine is widely used in surgery and obstetrics, attempts have been made to develop a safer long-acting local anaesthetic.
    The bupivacaine molecule is a racemic compound. Levobupivacaine is the S-enantiomer of bupivacaine and is thought to have less cardiotoxic potential than the R-enantiomer. The pharmacokinetic parameters of levobupivacaine are similar to those of bupivacaine.

    Levobupivacaine has been studied in surgical anaesthesia and for pain management. It can be used for local infiltration, epidural, intrathecal and peripheral nerve blocks. For epidural analgesia it can be given with clonidine. Double-blind comparisons of levobupivacaine and bupivacaine show that their anaesthetic effects are similar.

     

    Levobupivacaine Clinical Common usage

    Levobupivacaine is a local anaesthetic drug belonging to the amino amide group. It is the S-enantiomer of bupivacaine. Levobupivacaine hydrochloride is commonly marketed by Abbott under the trade name Chirocaine.

    Compared to bupivacaine, levobupivacaine is associated with less vasodilation and has a longer duration of action. It is approximately 13 percent less potent (by molarity) than racemic bupivacaine and has a longer motor block onset time. Levobupivacaine is indicated for local anaesthesia including infiltration, nerve block, ophthalmic, epidural and intrathecal anaesthesia in adults; and infiltration analgesia in children.

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