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Procaine HCL Brightness Powder Procaine Hydrochloride

Quick Detail: Procaine hydrochloride is a kind of local anesthetics.It can temporarily block the transmission of nerve fibers.Therefore,it has a nesthesia effect, strong function, low toxicity, and no addiction.Because its weak penetration through skin and mucous membrane,it is not suitable for...

  • Features & Specification

    Quick Detail:

    Product name

    Procaine hydrochloride

    Other name

    Procaine HCL

    CAS

    51-05-8

    MF

    C13H21ClN2O2

    MW;

    272.77

    Molecular structure

    image003.jpg

    Assay

    99.8%

    Appearance:

    White Fine Powder

    Usage

    Anti-Inflammatory Anesthetic   Anodyne 

    Procaine hydrochloride is a kind of local anesthetics.It can temporarily block the transmission of nerve fibers.Therefore,it has a nesthesia effect, strong function, low toxicity, and no addiction.Because its weak penetration through skin and mucous membrane,it is not suitable for surface anesthesia.it is mainly used for clinical infiltration, spine, and conduction block.

     

    Application: 

    Procaine HCl is a local anesthetic drug of the amino ester group. It is used primarily to reduce the pain of intramuscular injection of penicillin, and it is also used in dentistry. Owing to the ubiquity of the trade name Novocain, in some regions procaine is referred to generically as novocaine. It acts mainly by being a sodium channel blocker.Today it is used therapeutically in some countries due to its sympatholytic, anti-inflammatory, perfusion enhancing, and mood enhancing effects. 

    Procaine HCl is indicated for the production of local or regional analgesia and anesthesia by local infiltration and peripheral nerve block techniques. 

    Application of procaine leads to the depression of neuronal activity. The depression causes the nervous system to become hypersensitive producing restlessness and shaking, leading to minor to severe convulsions. Studies on animals have shown the use of procaine led to the increase of dopamine and serotonin levels in the brain.Other issues may occur because of varying individual tolerance to procaine dosage. Nervousness and dizziness can arise from the excitation of the central nervous system, which may lead to respiratory failure if overdosed. Procaine may also induce weakening of the myocardium leading to cardiac arrest. 

    Procaine can also cause allergic reactions causing the individuals to have problems with breathing, rashes, and swelling. Allergic reactions to procaine are usually not in response to procaine itself, but to its metabolite PABA. About one in 3000 people have an atypical form of pseudocholinesterase,[citation needed] which does not hydrolyze ester anesthetics such as procaine, resulting in a prolonged period of high levels of the anesthetic in the blood and increased toxicity.

     

    Procaine hydrochloride Function:
    A local anesthetic of the amino ester group that is primarily used as a topical anesthetic.Also used to control the pain of intramuscular injection of penicillin as well as in dentistry.Non Caine local anesthetic. 

    Procaine hydrochloride is a kind of local anesthetics, for local anesthesia, nerve block etc, can block the conduction of nerve fibers with anesthetic effect, strong function, low toxicity, and no addiction, but the skin, mucous membrane penetration force is weak, not suitable for surface anesthesia, clinically used to infiltration, spine and conduction anesthesia.

     

    Procaine hydrochloride COA: 

    ITEM

    Procaine Hydrochloride

    MF.G

    2015/08/28

    QUANTITY

    25KG

    OUTER PACKING

    Cardboard drum

    INNER PACKING

    Plastic bag

    STANDARD

    BP2005

    ITEM

    INDEX

    TEST

    APPEARANCE

    A white, crystalline powder

    A white, crystalline powder

    MELTING POINT

    154-158ºC

    154-157ºC

    IDENTIFICATION

    comply with the requirement

    confirms

    APPEARANCE OF SOLUTION

    Clear and coulorless

    Confirms

    IMPURITY

    Comply with 2,6-dimethylaniline

    Confirms

    PH

    5.0-6.5

    5.9

    MOISTURE

    5.5-7.0%

    6.67%

    SULPHATED ASH

    ≤0.1%

    0.02%

    HEAVY METALS

    ≤5ppm

    <5ppm

    PURITY

    ≥99.0-101.0%

    99.70%

    RESULT

    Confirms with BP2005 standard

     

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