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Pharmaceutical Anesthetic Pramoxine Hydrochloride

Pharmaceutical Anesthetic Pramoxine hydrochloride Pramoxine hydrochloride Main details Pramoxine hydrochloride is a local topical anesthetic. This anesthetic is available with or without menthol in cream form as well as gel form. It is used to relieve minor pain and inflammation of the skin...

  • Features & Specification

    Pharmaceutical Anesthetic Pramoxine hydrochloride

    Pramoxine hydrochloride Main details

    Pramoxine hydrochloride is a local topical anesthetic. This anesthetic is available with or without menthol in cream form as well as gel form. It is used to relieve minor pain and inflammation of the skin brought on by any number of factors. As with any medication or anesthetic, care should be taken while using pramoxine hydrochloride. 

    Product name

    Pramoxine hydrochloride

    CAS NO.

    637-58-1

    Appearance

    white crystalline powder

    Assay

    99%

    Usage

    1. muscle relaxant (smooth) 
    2. slows growth of unwanted facial hair 
    3. Local anesthetics 

    Pramoxine is used in the treatment of minor skin disorders. It can relieve pain and pruritus as well as inflammation associated with minor burns and sunburns. Pramoxine is also used to relieve inflammation and pain from insect bites, poison ivy, poison oak, minor cuts and scratches.

     

    Pramoxine hydrochloride Uses

    Pramoxine hydrochloride cream USP can be used by adults and adolescents as needed three to four times per day. The same dosing instructions can also be followed in the use of pramoxine hydrochloride lotion, pramoxine hydrochloride and menthol gel as well as pramoxine hydrochloride and menthol lotion. Proper dosing for pediatric use in children younger than two years old has not been established. Pramoxine should not be applied across large areas of the body and should not be used for extended periods of time as this may increase the risk of toxicity and systemic absorption.

     

    Certificate of analysis

    Item of analysis

    Specification

    Result

    Melting range

    170~174ºC

    171.7~173.2ºC

    Loss on drying

    <1.0%

    0.12%

    Residue on ignition

    <0.1%

    0.04%

    Ethanol

    <0.5%

    0.061%

    Carbinol

    <0.3%

    0.10%

    Acetone

    <0.5%

    Not detected

    Assay

    98.0%~102.0%

    99.98%

    Conclusion

    The results conforms with USP33

     

    More details about Proparacaine hydrochloride

    Proparacaine hydrochloride is indicated to produce local anesthesia prior to surgical procedures such as cataract extraction and pterygium excision, usually as an adjunct to locally injected anesthetics.

    Ophthalmic solutions used for intraocular procedures should be preservative free. Preservatives may cause damage to the corneal epithelium if a significant quantity of solutionenters the eye through the incision.

     

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