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Bupivacaine Hydrochloride with Dextrose Injection

Product introduction Best Bupivacaine hydrochloride Peptides Whatsapp:+8618123940985 Skype:shucanlynn Emial:demi@chembj.com Sample:Available Price: Negotiable Customized blend :Available Standard: SGS,ISO9001,KOSHER Name:Bupivacaine hydrochloride Whatsapp:+8618123940985 Synonyms:BUPIVACAINE...

  • Features & Specification

    Product introduction

    Best Bupivacaine hydrochloride Peptides

    Whatsapp:+86 18123940985

    Skype:shucanlynn

    Email:demi@chembj.com

    Sample:Available

    Price: Negotiable

    Customized blend :Available

    Standard: SGS,ISO9001,KOSHER

     

    Name:Bupivacaine hydrochloride 

    Whatsapp:+8618123940985

    image002.jpg

    CAS:14252-80-3
    MF:C18H28N2O.ClH
    MW:324.89
    Chemical Properties:White Solid 
    Bupivacaine hydrochloride Usage:antineoplastic,Sodium channel blocker, local anesthetic 

    Product   name

     Bupivacaine   hydrochloride

    CAS No

     14252-80-3

    EINECS   No

     241-917-8

     MF

     C18H31ClN2O2

     MW

     342.9

     Appearance

     White   crystal powder

     Purity

     98.5%~101.5%

     Ash

     0.1%   max

     Loss   on dry

     0.1%   max

     Heavy   Metal

     10ppm   max

     Package

     5/10kg   cardboard drum

     Standard

     USP   30


    Similar Local Anesthetic Powder: Benzocaine , Lidocaine hcl , Procaine hcl, Tetracaine hcl etc.
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    Bupivacaine Hydrochloride Description

    Bupivacaine hydrochloride is 2-Piperidinecarboxamide , 1-butyl-N-(2,6-dimethylphenyl)- , monohydrochloride , monohydrate , a white crystalline powder that is freely soluble in 95 percent ethanol , soluble in water , and slightly soluble in chloroform or acetone.

    Bupivacaine hydrochloride is available in sterile isotonic solutions with and without epinephrine (as bitartrate) 1 : 200 ,000 for injection via local infiltration, peripheral nerve block , and caudal and lumbar epidural blocks . Solutions of Bupivacaine Hydrochloride may be autoclaved if they do not contain epinephrine . Solutions are clear and colorless.


    Bupivacaine hydrochloride is related chemically and pharmacologically to the aminoacyl local anesthetics .They differ in this respect from the procaine-type local anesthetics , which have an ester linkage.

     

    Bupivacaine hydrochloride Use:
    Bupivacaine hydrochloride is related chemically and pharmacologically to the aminoacyl local anesthetics. It is a homologue of mepivacaine and is chemically related to lidocaine. All three of these anesthetics contain an amide linkage between the aromatic nucleus and the amino. They differ in this respect from the procaine-type local anesthetics, which have an ester linkage. 
    Bupivacaine hydrochloride injection, USP - Sterile isotonic solution containing sodium chloride. The pH of the solution is adjusted to between 4 and 6.5 with sodium hydroxide or hydrochloric acid. 

    Regional dosage

    Adults

    Up to 175 mg bupivacaine 0.25% as a single dose. May repeat once every 3 hours, do not exceed 400 mg in 24 hours.

     

    Bupivacaine Hydrochloride COA 

    Test Items

    Specification

    Test Results

    Appearance

    Fine, white, crystalline, odorless powder

    confirm

    Identification

    ABC in Pass

    confirm

    Solubility

    Free soluble in water and in alcohol; slightly   soluble in chloroform and in acetone

    confirm

    Melting point

    Melts at about 248 degree with decomposition

    confirm

    PH

    4.5_6.0

    5.16

    Related substance

    Not more than the reference solution 1.0%

    0.40%

    Heavy metals

    ≤ 0.001%

    < 0.001%

    Residue on ignition

    ≤ 0.10%

    0.047%

    Water

    4.0_6.0%

    5.0%

    Residual Solvents

    Alcohol ≤ 2.0%
      Isopropylic alcohol ≤ 2.0%

    Not detect

    Assay

    More Than 98.5 %

    99.51%

    Conclusion

    Confirms USP 32

     

    Bupivacaine Hydrochloride Usage: 

    Bupivacaine hydrochloride is related chemically and pharmacologically to the aminoacyl local anesthetics. It is a homologue of mepivacaine and is chemically related to lidocaine. All three of these anesthetics contain an amide linkage between the aromatic nucleus and the amino. They differ in this respect from the procaine-type local anesthetics, which have an ester linkage.

    Bupivacaine hydrochloride injection, USP - Sterile isotonic solution containing sodium chloride. The pH of the solution is adjusted to between 4 and 6.5 with sodium hydroxide or hydrochloric acid.

     

    Bupivacaine Hydrochloride Application: 

    Known side effects of the compound are increased aggression, disturbed sleep patterns or insomnia, high blood pressure and severe liver damage. It is highly dangerous if used by females. Some female side effects include severe acne, cessation of the menstrual cycle, deepening of the voice, clitoral enlargement and vaginal secretion. Effects of the drug will also be passed onto an unborn fetus.

     

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    Whatsapp:+86 18123940985

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