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Anti Pain Drugs Levobupivacaine 99% Purity

Anti Pain Drugs Levobupivacaine 99% Purity

Quick Detail: Product Name:Levobupivacaine CAS NO:27262-47-1 Assay:99% above Molecular Weight:288.428 Density:1.0 0.1 g/cm3 Boiling Point:423.4 45.0 C at 760 mmHg Molecular Formula:C18H29ClN2O Melting Point:254C (dec.)(lit.) Flash Point:209.9/28.7 C Appearance:White Powder Description and...

  • Features & Specification

    Quick Detail:

    Product Name:Levobupivacaine
    CAS NO:27262-47-1
    Assay:99% above
    Molecular Weight:288.428
    Density:1.0 0.1 g/cm3
    Boiling Point:423.4 45.0 C at 760 mmHg
    Molecular Formula:C18H29ClN2O
    Melting Point:254C (dec.)(lit.)
    Flash Point:209.9/28.7 C
    Appearance:White Powder

     

    Description and Application:

    Levobupivacaine is an amino-amide local anaesthetic drug belonging to the family of n-alkylsubstituted pipecoloxylidide. It is the S-enantiomer of bupivacaine.
    Compared with bupivacaine, levobupivacaine is associated with vasodilation and takes longer. It is about 13% more effective than racemic bupivacaine and has longer duration of block.
    Local anesthetics as a Levobupivacaine block production and transmission of nerve impulses, may be by increasing nerve electrical stimulation threshold, slows the transmission of nerve impulses, and lower the rising rate of the action potential. Generally, the progress of anesthesia is associated with the diameter of the affected nerve fibers, the myelin sheath and the conduction velocity. Specifically, the drug binds the cells of the sodium channel and blocks the flow of sodium into the nerve cells to prevent depolarization.

     

    Dosage for reference:
    Adults:
    Surgical anaesthesia epidural block: 50-100mg (using 0.5 % solution) or 75 to 150mg (using 0.75% solution).
    Cesarean section: 75-150 mg (using 0.5 percent solution). Spinal cord block: 15 mg (using 0.5 percent solution). Maximum: 150mg/dose; 400 mg/d.
    Peripheral nerve blocker 2.5-150mg or 1-2mg/kg (0.4ml/kg) 0.25 or 0.5 per cent solution. No more than 40ml. Maximum: 150mg/dose; 400 mg/d. Penetration anesthesia can be as high as 150 mg (with 0.25% solution).
    For the ball week in the program: 37.5-112.5mg (using 0.75% solution). Maximum: 150mg/dose; 400 mg/d.
    Pain relief in acute pain delivery: 15-50 mg (with 0.25% solution) as a dosing dose.
    Postoperative pain: 10 to 25 mg/h (with a 0.25% solution) as an epidural infusion. Maximum: 150mg/dose; 400 mg/d.

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